منابع مشابه
A Split Personality for Nucleosomes
A high-resolution look at where histones touch DNA reveals a surprisingly intricate, dynamic, and modular nucleosome. Three advances in the study by Rhee et al. include unexpected interactions between the H3 tail and linker DNA, new evidence for existence of subnucleosomal particles, and asymmetric patterns of histone modification within a single nucleosome that correspond to the direction of t...
متن کاملThe Split Personality of CENP-A Nucleosomes
The composition and structure of centromeric nucleosomes, which contain the histone H3 variant CENP-A, is intensely debated. Two independent studies in this issue, in yeast and human cells, now suggest that CENP-A nucleosomes adopt different structures depending on the stage of the cell cycle.
متن کاملSeamounts: identity crisis or split personality?
Less than 100 years after Mosely’s statement, Hubbs (1959) contemplated the ‘scientific interests, particularly in respect to zoogeography and speciation’ of recently discovered submerged mountains in the Pacific Ocean. Approximately 14,000 seamounts, undersea mountains peaking below sea level (Wessel, 2001; Kitchingman & Lai, 2004), rise up from the ocean bottom. Like terrestrial mountains (Br...
متن کاملOn the split personality of penultimate proline.
The influence of the position of the amino acid proline in polypeptide sequences is examined by a combination of ion mobility spectrometry-mass spectrometry (IMS-MS), amino acid substitutions, and molecular modeling. The results suggest that when proline exists as the second residue from the N-terminus (i.e., penultimate proline), two families of conformers are formed. We demonstrate the existe...
متن کاملThe split personality of regulatory T cells in HIV infection.
Natural regulatory T cells (Tregs) participate in responses to various chronic infections including HIV. HIV infection is associated with a progressive CD4 lymphopenia and defective HIV-specific CD8 responses known to play a key role in the control of viral replication. Persistent immune activation is a hallmark of HIV infection and is involved in disease progression independent of viral load. ...
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ژورنال
عنوان ژورنال: Frontiers in Ecology and the Environment
سال: 2020
ISSN: 1540-9295,1540-9309
DOI: 10.1002/fee.2281